DESCRIPTIONClarithromycin is often used in a wide variety of infections such as pneumonia, bronchitis, and infections of the lungs, ears, sinuses, skin, and throat. Therapy with antibiotics, such as clarithromycin, should last for two weeks in mild forms of disease. In individuals with decreased immunity or more severe Legionnaire's disease, antibiotic treatment should be taken for three weeks. Biaxin may cause side effects such as diarrhea, upset stomach, abnormal taste, stomach pain, and headache.
ORIGINAL USES (ON-LABEL)
Various infections.
NEWLY DISCOVERED USES (OFF-LABEL)
Legionnaire's disease, Lyme disease, prevention of bacterial endocarditis.
POTENTIAL SIDE EFFECTS
Headache, rash, abdominal pain, upset stomach, diarrhea, nausea, vomiting, abnormal taste, heartburn.
CAUTIONS
- Inform your doctor if you are allergic to macrolide antibiotics such as erythromycin, azithromycin.
- It should not be used in combination with ranitidine or bismuth citrate if you have a history of acute porphyria.
- Dosage adjustment is required with severe kidney impairment.
- Drugs in this class have been associated with various forms of abnormal heart rhythm, including QT prolongation, torsades de pointes.
- Use of antibiotics for prolonged periods may result in super infection.
- Safety and efficacy in children less than six months of age have not been established.
Astemizole, cisapride, gatifloxacin, moxifloxacin, pimozide, sparfloxacin, thioridazine, type Ia and III antiarrhythmic drugs, mesoridazine, alfentanil, benzodiazepines, buspirone, calcium channel blockers, carbamazepine, cilostazol, clozapine, colchicine, cyclosporine, digoxin, disopyramide, ergot alkaloids, HMG-CoA reductase inhibitors, loratadine, methylprednisolone, rifabutin, tacrolimus, theophylline, valproate, vinblastine, vincristine, zopiclone, sildenafil, tadalafil, vardenafil, neuromuscular blocking drugs, warfarin, amprenavir, zafirlukast, сlindamycin, lincomycin, zidovudine. This drug can potentially interact with many drugs. Consult with your pharmacist or doctor prior to starting prescription medications, herbals, or non-prescription drugs.
FOOD INTERACTIONS
Food delays absorption, but total absorption remains unchanged. May be taken with or without meals. May be taken with milk.
HERBAL INTERACTIONS
St John’s wort.
PREGNANCY AND BREAST-FEEDING CAUTIONS
FDA Pregnancy Risk Category C. It is not known if this drug is excreted in breast milk. Consult with your doctor.
SPECIAL INFORMATION
In a review article by a researcher with The Clinical Pharmacology Research Center in Cooperstown, New York, clarithromycin is among the list of recommended antibiotics for Legionnaire's disease. In a clinical study conducted by researchers in the United Kingdom, oral azithromycin (an antibiotic) given once daily was more effective than this drug in preventing fever and reducing the number of bacteria and lung lesions in guinea pigs. Researchers found that an eight-fold higher dose of Biaxin was needed to gain the same effect as low-dose azithromycin in this study. Finally, in a clinical study by researchers in Pakistan, use of Biaxin was associated with a 98% clinical cure rate in 34 patients with Legionnaire's disease. Researchers concluded that clarithromycin is a safe and effective treatment in patients with severe Legionnaire's disease that may be used in those who do not respond to azithromycin.
In those adults and children with risk factors for the disease such as congenital heart disease, heart valve surgery, dental surgery along with an allergy to penicillin (an antibiotic) Biaxin has been recommended by doctors to prevent streptococcal bacterial endocarditis. In a U.S. study conducted at the Mayo Clinic in Minnesota, the efficacy of clarithromycin and azithromycin was compared with other antibiotics in the prevention of endocarditis. In this study, rabbits induced with endocarditis were given one of the following regimens: no antibiotics or two doses of the following antibiotics: amoxicillin, azithromycin, clarithromycin. In this study, clarithromycin and azithromycin were as effective as amoxicillin, clindamycin, or erythromycin for the prevention of endocarditis.
Buy Biaxin
Where can I buy Biaxin without prescription?Biaxin tablets are a prescription drug that comes in 500 mg tablets. It is available on prescription only as tablets for oral use, but the online pharmacy, will sell Biaxin without prescription. You may be able to order Biaxin from them online and save the local pharmacy markup.
Whether I can pay my Biaxin order by Credit Card?
Pharmacies accept credit cards Visa and Mastercard, online checks (ACH), EuroDebit, Wire transfers.
Is the Biaxin purchase legal?
Yes, it is legal. You confirm, that buy Clarithromycin only for personal use without the purposes of resale. All medicines are solved for application in the majority of the countries. Biaxin drug should pass any customs house, including USA, without problems. If you have problems with customs house, inform pharmacy, they shall repeat (free-of-charge) your Clarithromycin order.
If I'm buying Biaxin online for the first time?
Buy generic Biaxin online after comparing prices to your local pharmacy and you'll agree - any drugstore can sell you Clarithromycin at a reduced cost.
What is Biaxin?
Clarithromycin, an antibiotic used in a wide variety of bacterial infections, blocks bacterial growth in bacterial endocarditis and is given preventively before medical procedures.
Clarithromycin, an antibiotic used in a wide variety of bacterial infections, blocks bacterial growth in bacterial endocarditis and is given preventively before medical procedures.
BRAND NAME
Biaxin
GENERIC NAME
Clarithromycin
CHEMICAL CLASS
Macrolide derivative.
THERAPEUTIC CLASS
Antibiotic (macrolide)
Biaxin
GENERIC NAME
Clarithromycin
CHEMICAL CLASS
Macrolide derivative.
THERAPEUTIC CLASS
Antibiotic (macrolide)
AVAIL FORMS
Tablets — Oral 500 mg.
Tablets — Oral 500 mg.
DOSAGE
Adult
Acute maxillary sinusitis: PO 500 mg bid x 14 days.
Acute exacerbation of chronic bronchitis: (due to Haemophilus) PO 500 mg bid x 7-14 days. (due to Moraxella, S. pneumoniae) PO 250 mg bid x 7-14 days.
Mycobacterial infections: PO 500 mg bid x 7-14 days.
Other infections: PO 250 mg bid for 7-14 days.
H. pylori: PO 500 mg bid x 10 days (with omeprazole 20 mg bid and amoxicillin 1 gm bid).
Dosing adjustment in renal impairment (CrCl <30 ml/min): decrease dose by 50% or double dosing interval.
Child
15 mg/kg/day divided q12h x 10 days
Mycobacterial infections: PO 7.5 mg/kg bid, do not exceed 500 mg bid.
Adult
Acute maxillary sinusitis: PO 500 mg bid x 14 days.
Acute exacerbation of chronic bronchitis: (due to Haemophilus) PO 500 mg bid x 7-14 days. (due to Moraxella, S. pneumoniae) PO 250 mg bid x 7-14 days.
Mycobacterial infections: PO 500 mg bid x 7-14 days.
Other infections: PO 250 mg bid for 7-14 days.
H. pylori: PO 500 mg bid x 10 days (with omeprazole 20 mg bid and amoxicillin 1 gm bid).
Dosing adjustment in renal impairment (CrCl <30 ml/min): decrease dose by 50% or double dosing interval.
Child
15 mg/kg/day divided q12h x 10 days
Mycobacterial infections: PO 7.5 mg/kg bid, do not exceed 500 mg bid.
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