Cocaine causes constriction of the coronary arteries, with a decrease in the blood flow. There can be a variety of problems in normal heart function including: arrhythmia, chest pain, or myocardial infarction. The majority of cocaine users are younger than 40, have no cardiac risk factors, and have no history of previous cardiopulmonary disorders.
Commonly Prescribed (On-Label) Drugs: None
Off-Label Prescription Drug Breakthrough Option: Nitroglycerin IV
One third of hospitalized patients in the United States, or about 12 million a year, receive heparin. Heparin-induced thrombocytopenia (HIT) occurs in three percent of patients who receive intravenous heparin for treatment of deep vein thrombosis or pulmonary embolism. Thrombocytopenia is a condition characterized by low platelet count. It occurs when platelets are lost from the circulation faster than they can be replaced from the bone marrow where they are made. This may result in you experiencing spontaneous bleeding. Low-molecular-weight heparin causes HIT less often (incidence, about 0.5%) than unfractionated heparin.
Commonly Prescribed (On-Label) Drugs: Argatroban, Lepirudin
Off-Label Prescription Drugs Breakthrough Options: Bivalirudin, Fondaparinux
Idiopathic edema refers to a disorder occurring in young, menstruating women in the absence of cardiac, hepatic, or renal disease. Fluid retention may initially occur premenstrually but often becomes persistent. Obesity and emotional problems (including depression and neurotic symptoms) are commonly part of this syndrome.
Commonly Prescribed (On-Label) Drugs: None
Off-Label Prescription Drug Breakthrough Option: Captopril
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