In aortic valve regurgitation, the aortic valve does not close properly. With each heartbeat, some of the blood pumped into the aorta leaks back (regurgitates) through the faulty valve into the left ventricle. The body doesn’t receive enough blood, so the heart must work harder to make up for it. Typically, symptoms do not develop for decades because the heart compensates by enlarging so that it can pump out more blood.
Commonly Prescribed (On-Label) Drugs: None
Off-Label Prescription Drug Breakthrough Option: Hydralazine
Mitral valve regurgitation, or mitral regurgitation, is a condition in which the mitral valve doesn’t close tightly, allowing blood to flow backward in the heart. When the mitral valve does not function properly, blood cannot move through the heart or to the rest of your body as efficiently. Mitral valve regurgitation is also called mitral insufficiency or incompetence. The condition frequently causes fatigue and shortness of breath.
Commonly Prescribed (On-Label) Drugs: None
Off-Label Prescription Drug Breakthrough Option: Nitroprusside
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