The gastrointestinal system is lined with delicate mucous membranes. Any damage to that lining, whether from ulcers, malignancies, or other disorders, can cause acute or chronic bleeding which needs to be treated and its recurrence prevented.

Acute Upper Gastrointestinal Bleeding

Acute upper gastrointestinal bleeding is a medical emergency. If the bleeding is not stopped with medication, surgery will be required. If the bleeding is not stopped by medical or surgical means, you are at serious risk of death.

Commonly Prescribed (On-Label) Drugs: None

Off-Label Prescription Drugs Breakthrough Options: Octreotide, Omeprazole, Vasopressin

Gastrointestinal Bleeding

Gastrointestinal bleeding is a symptom not a disorder. It may be caused by a wide range of problems including ulcers, varices (like varicose veins), cancer, benign tumors, injuries, infections, inflammation, colitis, or other causes. It is a particular problem in the intestines when the site of the bleeding cannot be located.

Commonly Prescribed (On-Label) Drugs: None

Off-Label Prescription Drug Breakthrough Option: Thalidomide

Prevention of Recurrence of Upper GI Bleeding

After upper gastrointestinal bleeding has been brought under control, your physician must assess whether this is a condition that is likely to occur again. If it is concluded that recurrence is likely, medical or surgical steps must be taken to prevent recurrence to help prevent another crisis.

Commonly Prescribed (On-Label) Drugs: None

Off-Label Prescription Drugs Breakthrough Options: Famotidine, Omeprazole, Pantoprazole, Ranitidine

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