DESCRIPTION
Famotidine belongs to a class of drugs called H2 blockers because it inhibits the action of histamine on cells that block acid secretion in the stomach. It is approved for the treatment of duodenal and gastric ulcers, dyspepsia and heartburn and their prevention, and other conditions related to stomach acid secretion. Studies have found that it is also effective in the prevention of recurrent upper gastrointestinal bleeding.

ORIGINAL USES (ON-LABEL)
Treatment of duodenal ulcer, benign gastric ulcer, gastroesophageal reflux disease (GERD), pathological hypersecretory conditions.

NEWLY DISCOVERED USES (OFF-LABEL)
Chemotherapy induced (prevention) anaphylaxis, prevention of recurrence of upper gastrointestinal (GI) bleeding.

POTENTIAL SIDE EFFECTS
Headache, dizziness, dry mouth.

CAUTIONS
  • May require reduced doses if you have impaired kidney function.
  • Injectable form (multidose vials) contains benzyl alcohol.
  • The efficacy and safety of this drug in children has not been studied by the manufacturer.
DRUG INTERACTIONS
  • Cefpodoxime, cefuroxime, enoxacin, ketoconazole: Reduction in gastric acidity reduces absorption, decreased plasma levels, potential for therapeutic failure.
  • Glipizide; glyburide; tolbutamide: Increased absorption of these drugs, potential for hypoglycemia.
  • Nifedipine; nitrendipine; nisoldipine: Increased concentrations of these drugs.


    • FOOD INTERACTIONS
    Alcohol. May be taken without regard to meals.

    HERBAL INTERACTIONS
    Unknown.

    PREGNANCY AND BREAST-FEEDING CAUTIONS
    FDA Pregnancy Risk Category B. Excreted in breast milk. Breast-feeding not recommended due to limited human data.

    SPECIAL INFORMATION
  • Drug must be continued for prescribed time in prescribed method to be effective; do not double dose.
  • Possibility of decreased libido, reversible after discontinuing therapy.
  • Smoking should be avoided; diminishes effectiveness of medication.
  • Avoid tasks requiring alertness; dizziness, drowsiness may occur.

    • An article in Alimentary Pharmacological Therapy from the Kawasaki Medical School in Japan reported on a study of famotidine versus omeprazole in the treatment of bleeding peptic ulcer. They divided 400 people to take one of the two therapies, given by intravenous infusion, and monitored the duration of fasting, hospital stay, volume of transfused blood, recurrences of bleeding, and death. While bleeding recurrences were not significantly different, the average hospital stay was significantly shorter in the omeprazole group (18.4 days) than in the famotidine group (21.5 days). However there was no significant difference in the other symptoms. Researchers conclude that the two drugs are equivalent for prevention of recurrent bleeding.

    Buy Pepcid

    Where can I buy Pepcid without prescription?
    Famotidine drug is a prescription drug that comes in 20 mg, 40 mg tablets. It is available on prescription only as tablets for oral use, but the online drug store, will sell Pepcid without prescription. Packs containing no more than two weeks' supply of tablets, for the relief of indigestion and heartburn in people over 16 years old, can be obtained from pharmacies without a script. You may be able to order Pepcid from them online and save the local pharmacy markup.

    Whether I can pay my Pepcid order by Credit Card?
    Pharmacies accept credit cards Visa and Mastercard, online checks (ACH), EuroDebit, Wire transfers.

    Is the Pepcid purchase legal?
    Yes, it is legal. You confirm, that buy Famotidine only for personal use without the purposes of resale. All medicines are solved for application in the majority of the countries. Pepcid Drug should pass any customs house, including USA, without problems. If you have problems with customs house, inform pharmacy, they shall repeat (free-of-charge) your Pepcid order.

    If I'm buying Pepcid online for the first time?
    Buy generic Pepcid online after comparing prices to your local pharmacy and you'll agree - any drugstore can sell you Famotidine medication at a reduced cost.

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    What is Pepcid?
    This drug inhibits gastric acid secretion.
    BRAND NAME
    Pepcid

    GENERIC NAME
    Famotidine

    CHEMICAL CLASS
    Thiazole derivative

    THERAPEUTIC CLASS
    Antiulcer agent; Antihistamine, gastric ulcer (H2 blocker; histamine H2 antagonist)

    AVAIL FORMS
    Tablets — Oral 20 mg, 40 mg.
    DOSAGE
    Adult
    Duodenal ulcer: PO 40 mg every day hs x 4-8 week, then 20 mg daily hs if needed (maintenance).
    Gastric ulcer: PO 40 mg qhs.
    GERD: PO 20 mg twice a day for up to 6 week; for esophagitis due to GERD, 20-40 mg twice a day for up to 12 week.
    Hypersecretory conditions: PO 20 mg every 6 hours; may give 160 mg q6h if needed.
    Heartburn, acid indigestion, and sour stomach (OTC): PO 10 mg twice a day as needed; for prevention of heartburn, take 1 hour before meals.
    Renal failure (CrCl <10 ml/min): PO 20 mg qhs or increase dosing interval to 36-48 hour.

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