DESCRIPTION
Fluticasone works directly in the lungs to make breathing easier by reducing the swelling and inflammation of the airways. This medication must be used regularly to prevent the wheezing and shortness of breath caused by asthma, bronchitis, or some types of emphysema.

ORIGINAL USES (ON-LABEL)
Inhalation: Maintenance treatment of asthma as preventive therapy. It is also indicated for patients requiring oral corticosteroid therapy for asthma to assist in total discontinuation or reduction of total oral dose.

NEWLY DISCOVERED USES (OFF-LABEL)
Cystic fibrosis

POTENTIAL SIDE EFFECTS
Oral inhalation: Headache, fever, nausea/ vomiting, viral gastric infection, diarrhea, abdominal discomfort/pain, muscle injury, musculoskeletal pain, back problems, upper respiratory tract infection, throat irritation, nasal congestion, sore throat, viral infection.

Nasal inhalation: Headache, sore throat, nausea/vomiting, epistaxis, asthma symptoms, cough, aches and pains, flu-like symptoms.

CAUTIONS
  • Inhaled fluticasone should not be used for primary treatment of acute asthma attacks.
  • May cause hypercorticism or suppression of hypothalamic-pituitary-adrenal (HPA) axis, particularly in younger children or in patients receiving high doses for prolonged periods. HPA axis suppression may lead to adrenal crisis.
  • Particular care is required if you are being transferred from oral or injection corticosteroids to inhaled products due to possible adrenal insufficiency or withdrawal from steroids, including an increase in allergic symptoms.
  • Concurrent use of ritonavir (and potentially other strong inhibitors of specific liver enzymes) may increase fluticasone levels and effects on HPA suppression.
  • Controlled clinical studies have shown orally-inhaled and intranasal corticosteroids may cause a reduction in growth velocity in children.
  • May suppress the immune system, so you may be more susceptible to infection. Use with caution, if you use this drug at all, if you have systemic infections, active or quiescent tuberculosis infection or ocular herpes simplex. Avoid exposure to chickenpox and measles.
  • Flovent Rotadisk contains lactose; very rare allergic reactions have been reported in patients with severe milk protein allergy.
DRUG INTERACTIONS
Ketoconazole, ritonavir.

FOOD INTERACTIONS
Unknown

HERBAL INTERACTIONS
St. John's wort

PREGNANCY AND BREAST-FEEDING CAUTIONS
FDA Pregnancy Risk Category C. Excretion in breast milk unknown. Consult your doctor.

SPECIAL INFORMATION
Fluticasone is not indicated for the relief of acute bronchospasm. The inhaled products have a black box warning which describe the need for special care in patients who are transferred from systemic (oral or injectable) steroids to inhaled products that are less absorbed. A sudden decrease in dose due to lesser absorption may result in fatal suppression of the hypothalamus-pituitary-adrenal function and cause an adrenal crisis. This particularly applies to patients that are maintained on at least 20 mg daily (or its equivalent).

Inhaled fluticasone propionate is widely used to reduce lung inflammation in chronic obstructive pulmonary disease, but the potential effects of fluticasone propionate on airway cells from patients with Cystic Fibrosis (CF) are unknown. In CF, an inflammatory lung response occurs through a defective protein that makes the body susceptible to the bacteria Pseudomonas aeruginosa, which causes the airway to become filled with a thick mucus. The presence of these bacteria in the body leads to a chronic inflammation that further damages the lung cell surface.

Corticosteroids such as fluticasone have long-term benefits in suppressing the potentially damaging inflammatory response within the airways of patients with CF. Fluticasone proprionate is especially helpful in children with cystic fibrosis who are wheezy and have associated asthma. A study conducted in France found that this drug exerts an antiinflammatory effect by blocking a signal leading to a reduced level in lung cells.

Buy Flonase online

Where can I buy Flonase without prescription?
Fluticasone is a prescription drug that comes in 50 mcg nasal sprays. It is available on prescription only as nasal sprays, but the online pharmacy, will sell Fluticasone without prescription. You may be able to order Flonase from them online and save the local pharmacy markup.

Whether I can pay my Fluticasone order by Credit Card?
Pharmacies accept credit cards Visa and Mastercard, online checks (ACH), EuroDebit, Wire transfers.

Is the Fluticasone purchase legal?
Yes, it is legal. You confirm, that buy Flonase nasal spray only for personal use without the purposes of resale. All medicines are solved for application in the majority of the countries. Generic Fluticasone should pass any customs house, including American, without problems. If you have problems with customs house, inform pharmacy, they shall repeat (free-of-charge) your Fluticasone order.

If I'm buying Flonase online for the first time?
Buy Flonase online after comparing prices to your local pharmacy and you'll agree - any drugstore can sell you generic cheap Flonase at a reduced cost.

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What is Flonase?
This drug has medium potency as an anti-inflammatory drug, and has some limited ability to suppress adrenal secretions when applied topically. Inhaled fluticasone's effectiveness is due to its direct local effect.
BRAND NAME
Flovent, Flovent HFA, Flovent Rotadisk, Flonase

GENERIC NAME
Fluticasone

CHEMICAL CLASS
Corticosteroid, synthetic

THERAPEUTIC CLASS
Corticosteroid (inhalant or nasal spray)
AVAIL FORMS
Spray - Nasal 50 mcg (0.05 mg/inh).
DOSAGE
Adult
Allergic rhinitis: NASAL 1-2 sprays in each nostril qd or 1 spray in each nostril bid or bid prn; do not exceed 2 sprays/nostril/day.
Children
Allergic rhinitis: NASAL, children >4 yr, 1 spray in each nostril qd; may increase to 2 sprays in each nostril qd.

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