Hemosiderosis is a rare, often fatal, condition in which iron builds up in the lungs. The iron is in the form of hemosiderin, a pigment in blood. Hemosiderosis results from bleeding into the lungs, also known as pulmonary hemorrhage. Pulmonary hemosiderosis is often broken down into four categories: (1) idiopathic (unknown cause), (2) occurs along with pancreatic or heart disease, (3) occurs along with a milk sensitivity, and (4) occurs along with a kidney disease called glomerulonephritis.
Commonly Prescribed (On-Label) Drugs: None
Off-Label Prescription Drug Breakthrough Option: Prednisone
Sickle cell disease affects the red blood cells. Normal red blood cells are smooth and round like doughnuts. They move easily through blood vessels to carry oxygen to all parts of the body. In sickle cell anemia, the red blood cells become hard, sticky, and shaped like sickles or crescents. When these hard and pointed red cells go through the small blood vessels, they tend to get stuck and block the flow of blood. This can cause pain, damage, and a low blood count or anemia.
Commonly Prescribed (On-Label) Drugs: Hydroxyurea
Off-Label Prescription Drug Breakthrough Option: Ticlopidine
Pruritus affects 50-90% of patients undergoing dialysis. Symptoms such as mild itching usually begin about six months after the start of dialysis and range from localized and mild to generalized and severe. Uremic pruritus is poorly understood; possibilities include thyroid disorder, allergy, and iron-deficiency anemia, or some combination of these.
Commonly Prescribed (On-Label) Drugs: None
Off-Label Prescription Drugs Breakthrough Options: Epoetin Alpha, Ondansetron
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