White blood cell disorders are those diseases affecting the cells in blood that fight infection. White blood cells are produced by bone marrow. Disorders involving white blood cells include leukemia, a cancer of the blood, and neutropenia, a disorder that causes lower than normal levels of neutrophils, a type of white blood cell.
Agranulocytosis is a condition characterized by an insufficient number of white blood cells called neutrophils or granulocytes. This can be caused by a failure of the bone marrow to make sufficient neutrophils, or when white blood cells are destroyed faster than they can be produced. You may be more susceptible to infections due to this disorder.
Commonly Prescribed (On-Label) Drugs: None
Off-Label Prescription Drugs Breakthrough Options: Filgrastim, Sargramostim
Neutropenia is an abnormally low number of neutrophils (white blood cells that fight infection) in the blood. Neutrophils serve as the major defense of the body against acute bacterial and certain fungal infections. Neutrophils usually constitute about 45 to 75% of all white blood cells in the bloodstream. When the neutrophil count falls below 1,000 cells per microliter of blood, the risk of infection increases somewhat; when it falls below 500 cells per microliter, the risk of infection increases greatly. Without the key defense provided by neutrophils, you may have problems controlling infections and are at risk of dying from an infection.
Commonly Prescribed (On-Label) Drugs: Cefepime, Ciprofloxacin, Filgrastim, Itraconazole, Mezlocillin, Pegfilgrastim, Sargramostim
Off-Label Prescription Drug Breakthrough Option: Lithium
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