Sexually transmitted diseases (STDs) are bacterial or viral infections that are acquired through sexual contact with an infected person. Usually, STDs are passed through sexual intercourse; however, they can also be passed through other forms of sex. Anyone who is sexually active is at risk for having an STD. The risk for STDs increases if a person has multiple sex partners or unprotected sex (without a condom). Symptoms of STDs vary according to the specific infection. STDs include chancroid, chlamydia, granuloma inguinale, herpes simplex, lymphoma venereum, and syphilis.
Chancroid is a sexually transmitted genital ulcer disease that is caused by the bacteria Haemophilus ducreyi. Chancroid is characterized by painful ulcers and swelling and/or inflammation of the lymph nodes in the groin, and is spread by sexual contact. Symptoms of chancroid generally appear within one week after exposure to the bacteria. They are often less noticeable in women and may be limited to painful urination or defecation, painful sexual intercourse, rectal bleeding, or vaginal discharge.
Off-Label Prescription Drug Breakthrough Option: Erythromycin
Chlamydia is a sexually transmitted diseases (STD) caused by the bacteria known as Chlamydia trachomatis. It is one of the most wide spread bacterial STDs in the United States and is acquired through oral, vaginal, or anal sexual contact with an infected person. The bacteria that cause chlamydia live in the semen and vaginal fluid, and infected persons may or may not have symptoms of infection. Symptoms generally occur within one to three weeks after infection and can include abnormal mucus or pus from the vagina or penis or pain during urination.
Commonly Prescribed (On-Label) Drugs: Erythromycin, Ofloxacin, Sulfadiazine, Sulfamethoxazole, Sulfisoxazole
Off-Label Prescription Drugs Breakthrough Options: Azithromycin, Doxycycline
Granuloma inguinale is a bacterial sexually transmitted disease (STD) that is caused by the organism Calymmatobacterium granulomatis. Granuloma inguinale is often found in tropical and subtropical regions. Symptoms include a small, beefy-red bump on the genitals or perianal area that gradually eats away at the skin and forms an elevated, beefy-red, velvety nodule. Nodules are often painless and can bleed easily if traumatized. Other symptoms include spread of the disease to where the leg meets the torso and loss of skin color of the genitals. If untreated, granuloma inguinale can destroy the genital tissue.
Commonly Prescribed (On-Label) Drugs: Streptomycin
Off-Label Prescription Drugs Breakthrough Options: Ciprofloxacin, Erythromycin, Trimethoprimsulfamethoxazole
In lymphogranuloma venereum, a sexually transmitted disease (STD) caused by the bacteria Chlamydia trachomatis, inflammation and drainage of certain lymph nodes and destruction and scarring of surrounding tissue occurs. Symptoms of lymphogranuloma venereum include a small, painless ulcer on the genitals, swelling or redness of the skin in the groin, swollen groin lymph nodes, drainage from inguinal lymph nodes, drainage of blood or pus from the rectum, and pain during bowel movements. The main risk factor is having multiple sexual partners.
Commonly Prescribed (On-Label) Drugs: Doxycycline, Tetracycline
Off-Label Prescription Drug Breakthrough Option: Erythromycin
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