(mag-NEE-zhum SUL-fate)
Injection
NEWLY DISCOVERED USES (OFF-LABEL)
Cardiac arrest, premature labor (preterm), migraine treatment, tachycardia in children, Torsades de Pointes, ventricular tachycardia
ORIGINAL USES (ON-LABEL)
Treatment and prevention of low magnesium levels, seizure prevention in severe pre-eclampsia or eclampsia, pediatric acute nephritis (inflammation of the kidney)
BRAND NAME
Magnesium Sulfate
DRUG CLASS
Electrolyte supplement (injection)
DESCRIPTION
When taken orally, magnesium promotes bowel evacuation by expanding the colon. When given by injection, magnesium decreases the level of a certain neurotransmitter in the body's motor nerve terminals and acts on the muscular tissue of the heart to strengthen the heart's performance.
POTENTIAL SIDE EFFECTS
Changes in blood pressure and heart rate with rapid administration. Flushing, sweating, depressed reflexes, flaccid paralysis, low temperatures, cardiac and central nervous system (CNS) depression.
CAUTIONS
- Inform your doctor if you have heart disease or damage, kidney or liver problems, myasthenia gravis, other neuromuscular disease, or Addison's disease.
- Requires monitoring of serum magnesium level, respiratory rate, deep tendon reflex, and kidney function.
DRUG INTERACTIONS
Neuromuscular blockers (such as tubocurarine, vecuronium, succinylcholine).
FOOD INTERACTIONS
Unknown
HERBAL INTERACTIONS
Unknown
PREGNANCY AND BREAST-FEEDING CAUTIONS
This information does not apply to oral formulations.
SPECIAL INFORMATION
This information pertains to the use of the prescription product only and should not be inferred for the use of nonprescription formulations.
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