DESCRIPTION
Pantoprazole is a proton pump inhibitor that stops the production and release of gastric acid in the stomach, thereby decreasing acid production and allowing the stomach and esophagus to heal. Side effects include diarrhea, headache, stomach pain, and gas or bloating.

ORIGINAL USES (ON-LABEL)
Short-term treatment of active duodenal ulcers; maintenance treatment of healed duodenal ulcers, part of H. pylori treatment regimen, treatment of gastric ulcer, gastroesophageal reflux disease (GERD), erosive esophagitis.

NEWLY DISCOVERED USES (OFF-LABEL)
Laryngitis, stress-related mucosal disease, prevention of recurrence of upper gastrointestinal (GI) bleeding.

POTENTIAL SIDE EFFECTS
Diarrhea, abdominal pain, abnormal dreams.

CAUTIONS
  • Dosage reductions may be required if you have severe liver dysfunction.
  • Inform your doctor if you have allergies to any drugs in this class.
  • Long-term treatment has resulted in atrophic gastritis.
  • Absorption may be increased in the elderly.
  • Relief of symptoms with use of this drug does not exclude gastric cancer.
DRUG INTERACTIONS
Minimize risk
Ketoconazole: Decreased bioavailability of ketoconazole
  • Increased pantoprazole serum levels: diazepam, phenytoin, flurazepam, triazolam, clarithromycin.
  • Increased bleeding: warfarin.
  • May decrease absorption: sucralfate.


    • FOOD INTERACTIONS
    Avoid alcohol.

    HERBAL INTERACTIONS
    St. John's wort, ginkgo biloba

    PREGNANCY AND BREAST-FEEDING CAUTIONS
    FDA Pregnancy Risk Category B. Excreted in breast milk. Therapy not recommended during breast-feeding.

    SPECIAL INFORMATION
    Antacids may be taken during therapy with this drug.

    Pantoprazole has been studied for the treatment of laryngitis in two clinical trials involving 51 adults. In these studies, Protonix alone was administered and then given in combination with cisapride (a prokinetic drug). In the study using a high-dose of pantoprazole with cisapride in 22 patients with gastroesophageal reflux disease (GERD)-related laryngitis, patients had significant reductions in all laryngitis symptoms. In another study of 29 patients with persistent hoarseness and voice disorders, Protonix was given once daily for six weeks. After six weeks of treatment, significant reductions in hoarseness, heartburn, sore throat, and indigestion were noticed. Moreover, after three months of treatment, these effects remained.

    Buy Protonix online

    Where can I buy Protonix without prescription?
    Protonix drug is a prescription medication that comes in 20 mg, and 40 mg tablets. It is prescription-only, but the internet drugstore, will sell Pantoprazole without prescription. You may be able to order Protonix from them online and save the local pharmacy markup.

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    What is Protonix?
    Pantoprazole tablets decrease gastric acid secretion by blocking the final step in gastric acid production.
    BRAND NAME
    Protonix

    GENERIC NAME
    Pantoprazole

    CHEMICAL CLASS
    Benzimidazole derivative

    THERAPEUTIC CLASS
    Gastrointestinal (proton pump inhibitor)

    AVAIL FORMS
    Tablets — Oral 20 mg, 40 mg.
    DOSAGE
    Adult
    PO 40 mg every day taken before or with breakfast.

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