DESCRIPTION
A substance that can coat and stick to mucous membranes. It has a cytoprotectant action, forming a barrier between peptic ulcers and the stomach acid, which allows the ulcers to heal. It is also used for the prevention of gastric bleeding due to stress ulceration in seriously ill patients, and can be used as mouthwash to coat sore patches or mouth ulcers, especially in people who have mouth problems due to radiotherapy or chemotherapy.

ORIGINAL USES (ON-LABEL)
Short-term management of duodenal ulcers, maintenance of duodenal ulcers.

NEWLY DISCOVERED USES (OFF-LABEL)
Esophagitis, gastric ulcer, NSAID-induced ulcer, prevention of cancer treatment-induced mucositis/stomatitis, prevention of gastric ulcer, stress related mucosal disease, vaginal ulceration.

MECHANISM OF ACTION
Forms a complex that adheres to ulcer site, protects against acid, pepsin, bile salts.

POTENTIAL SIDE EFFECTS
Constipation, nausea, indigestion, dizziness, headache, rash.

CAUTIONS
  • Notify your doctor if you have impaired kidney function or are on dialysis.
  • May alter the absorption of some drugs.
DRUG INTERACTIONS
Digoxin, phenytoin, warfarin, ketoconazole tablets, quinidine, tetracycline, theophylline, cimetidine, fluoroquinolone antibiotics (such as ciprofloxacin, levofloxacin, etc.), l-thyroxine, ranitidine. Administer drugs two hours before giving sucralfate.

FOOD INTERACTIONS
Decreased absorption of vitamin A, vitamin D, vitamin E and vitamin K

HERBAL INTERACTIONS
Unknown.

PREGNANCY AND BREAST-FEEDING CAUTIONS
FDA Pregnancy Risk Category B. Excreted in breast milk. Consult your doctor.

SPECIAL INFORMATION
  • Take antacids as needed for pain relief, but not within ? hour before or after sucralfate.

    • The American Journal of Medicine reported on a maintenance regimen of sucralfate to help reduce the relapse rate for duodenal ulcer disease. They divided patients with recently healed duodenal ulcers to receive this drug, cimetidine or placebo. After one year, 96 patients were examined by endoscopy (a small camera that is inserted through the mouth so a physician can see the esophagus, stomach, and duodenum). According to researchers, ulcers had recurred in 17 of 31 Carafate patients, 19 of 32 cimetidine patients, and 28 of the placebo patients. The investigators concluded that this medication was at least as effective as cimetidine in preventing duodenal ulcer relapse. Further, referring to the prior remission study, the investigators noted that patients initially treated with cimetidine alone had a greater early relapse rate than those treated with Carafate alone, a combination of sucralfate and cimetidine, or an antacid alone.

    Buy Carafate

    Where can I buy Carafate without prescription?
    Sucralfate tablets is a prescription drug that comes in 1 gm tablets. It is available on prescription only as tablets for oral use, but the online pharmacy, will sell Carafate without prescription. You may be able to order Carafate from them online and save the local pharmacy markup.

    Whether I can pay my Carafate order by Credit Card?
    Pharmacies accept credit cards Visa and Mastercard, online checks (ACH), EuroDebit, Wire transfers.

    Is the Carafate purchase legal?
    Yes, it is legal. You confirm, that buy Sucralfate only for personal use without the purposes of resale. All medicines are solved for application in the majority of the countries. Carafate Drug should pass any customs house, including American, without problems. If you have problems with customs house, inform drugstore, they shall repeat (free-of-charge) your Carafate order.

    If I'm buying Carafate online for the first time?
    Buy generic Carafate online after comparing prices to your local pharmacy and you'll agree - any online pharmacy can sell you Carafate medication at a reduced cost.

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    What is Carafate?

    This drug affects proteins to form a paste-like, adhesive substance which acts as a coating that protects the stomach lining against pepsin, peptic acid and bile salts.
    BRAND NAME
    Carafate

    GENERIC NAME
    Sucralfate

    CHEMICAL CLASS
    Aluminum complex of sulfated sucrose

    THERAPEUTIC CLASS
    Antiulcer agent, Gastrointestinal.

    AVAIL FORMS
    Tablets — Oral 1 g (gm).
    DOSAGE
    Adult
    Active ulcer: PO 1 gm four times a day 1 hour before meals and at bedtime for 4-8 week.
    Maintenance: PO 1 gram twice a day.

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