Nephrotic conditions are damage to the tiny blood vessels of the kidney that filter waste and excess water from the blood. They include nephrotic syndrome and membranous nephropathy.
In nephrotic syndrome, people have very high levels of protein in the urine but very low levels of protein in the blood and high cholesterol. It results from damage to tiny blood vessels in the kidneys that filter waste and excess water from the blood and send them to the bladder as urine. The syndrome may be congenital in children, arise for no known cause, or develop secondary to some other disorder.
Commonly Prescribed (On-Label) Drugs: Betamethasone, Bumetanide, Cortisone, Cyclophosphamide, Dexamethasone, Furosemide, Hydrocortisone, Methylprednisolone, Prednisolone, Prednisone, Spironolactone, Triamcinolone
Off-Label Prescription Drugs Breakthrough Options: Chlorambucil, Cyclosporine, Levamisole
Membranous nephropathy involves inflammation of the tiny blood vessels (glomeruli) that filter waste and excess water in the kidneys. They disrupt kidney function due thickening of the blood vessel walls in the glomerular basement membrane (the boundary between blood and urine). Usually, physicians do not know the cause, although in 30% of cases it may be secondary to some other disorder. It is an immunologically mediated disease. Membranous nephropathy is the most common cause of nephrotic syndrome in adults.
Commonly Prescribed (On-Label) Drugs: Prednisolone
Off-Label Prescription Drugs Breakthrough Options: Atorvastatin, Simvastatin, Chlorambucil, Cyclosporine, Enalapril, Lisinopril, Furosemide, Ibuprofen, Ketoprofen, Naproxen, Methylprednisolone
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